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The antibody against TRHDE was raised in rabbit using the Recombinant Human Thyrotropin-releasing hormone-degrading ectoenzyme protein (62-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against TRHDE was raised in rabbit using the Recombinant Human Thyrotropin-releasing hormone-degrading ectoenzyme protein (62-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human liver cancer using TRHDE Antibody at dilution of 1:1002
| Cat.No | ADC-16394A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRHDE |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Thyrotropin-releasing hormone-degrading ectoenzyme protein (62-200AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UKU6 |
Uniprot Id
Q9UKU6
Target Species
Human
Target Name
TRHDE
Target Full Name
Thyrotropin-releasing hormone-degrading ectoenzyme
Target Function
Specific inactivation of TRH after its release.
Target Subcellular Location
Membrane; Single-pass type II membrane protein.
Target Protein Families
Peptidase M1 family
Target Tissue Specificity
Predominantly expressed in brain.
Target Synonyms
TRHDE; UNQ2507/PRO5995; Thyrotropin-releasing hormone-degrading ectoenzyme; TRH-DE; TRH-degrading ectoenzyme; EC 3.4.19.6; Pyroglutamyl-peptidase II; PAP-II; TRH-specific aminopeptidase; Thyroliberinase
Target Background
This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.
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