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The antibody against TRHR was raised in rabbit using the Recombinant Human Thyrotropin-releasing hormone receptor protein (320-398AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against TRHR was raised in rabbit using the Recombinant Human Thyrotropin-releasing hormone receptor protein (320-398AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
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| Cat.No | ADC-06744A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRHR |
| Target Synonyms | TRHR; Thyrotropin-releasing hormone receptor; TRH-R; Thyroliberin receptor | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Thyrotropin-releasing hormone receptor protein (320-398AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P34981 |
Uniprot Id
P34981
Target Species
Human
Target Name
TRHR
Target Full Name
Thyrotropin-releasing hormone receptor
Target Function
Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Synonyms
TRHR; Thyrotropin-releasing hormone receptor; TRH-R; Thyroliberin receptor
Target Background
This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance.
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