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The antibody against TRIM26 was raised in rabbit using the Recombinant Human Tripartite motif-containing protein 26 protein (151-270AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against TRIM26 was raised in rabbit using the Recombinant Human Tripartite motif-containing protein 26 protein (151-270AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-04112A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRIM26 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tripartite motif-containing protein 26 protein (151-270AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q12899 |
Uniprot Id
Q12899
Target Species
Human
Target Name
TRIM26
Target Full Name
Tripartite motif-containing protein 26
Target Function
E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
TRIM/RBCC family
Target Synonyms
Acid finger protein; AFP; CAM25547; RING finger protein 95; RNF95; TRI26_HUMAN; TRIM26; tripartite motif containing 26 ; Tripartite motif-containing protein 26; widely expressed acid zinc finger protein ; Zinc finger protein 173; Zinc finger protein 173; formerly; ZNF173; ZNF173; formerly
Target Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
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