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Rabbit anti-Human TRIM54 Polyclonal Antibody

The antibody against TRIM54 was raised in rabbit using the Recombinant Human Tripartite motif-containing protein 54 protein (60-358AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-10139A

The antibody against TRIM54 was raised in rabbit using the Recombinant Human Tripartite motif-containing protein 54 protein (60-358AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

$299.00

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Specifications


Cat.No ADC-10139A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTRIM54
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Tripartite motif-containing protein 54 protein (60-358AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9BYV2
Background Information
  • Uniprot Id

    Q9BYV2

  • Target Species

    Human

  • Target Name

    TRIM54

  • Target Full Name

    Tripartite motif-containing protein 54

  • Target Function

    May bind and stabilize microtubules during myotubes formation.

  • Target Subcellular Location

    Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line.

  • Target Tissue Specificity

    Specifically expressed in heart and skeletal muscle.

  • Target Synonyms

    MURF 3; MuRF; MURF-3; MuRF3; Muscle specific RING finger protein 3; Muscle specific RING finger protein; Muscle specific RING finger protein homolog; Muscle-specific RING finger protein 3; Muscle-specific RING finger protein; RING finger protein 30; RNF30; TRI54_HUMAN; TRIM 54; Trim54; Tripartite motif containing 54 ; Tripartite motif containing protein 54; Tripartite motif-containing protein 54

  • Target Background

    The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

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