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The antibody against TRMT61A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human TRMT61A (NP_689520.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against TRMT61A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human TRMT61A (NP_689520.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-01654A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRMT61A |
| Target Synonyms | GCD14; TRM61; Gcd14p; hTRM61; C14orf172; TRMT61A | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, Mouse spleen, PC-3, Rat testis, U-251MG | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human TRMT61A (NP_689520.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96FX7 | Immunogen Sequence |
Uniprot Id
Q96FX7
Target Species
Human
Target Name
TRMT61A
Target Full Name
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A
Target Function
Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries.
Target Subcellular Location
Nucleus.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, TRM61 family
Target Synonyms
TRMT61A; C14orf172; TRM61; tRNA; adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; EC 2.1.1.220; mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A; EC 2.1.1.-; tRNA(m1A58)-methyltransferase subunit TRMT61A; tRNA(m1A58)MTase subunit TRMT61A
Target Background
Enables mRNA (adenine-N1-)-methyltransferase activity. Involved in mRNA methylation. Predicted to be located in nucleoplasm. Predicted to be part of tRNA (m1A) methyltransferase complex. Predicted to be active in nucleus.
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