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The antibody against TROP-2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-274 of human TROP-2 (NP_002344.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, FC, ELISA.
The antibody against TROP-2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-274 of human TROP-2 (NP_002344.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, FC, ELISA.
| Cat.No | ADA-15670A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TROP-2 |
| Target Synonyms | EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; TROP-2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | MCF7 | Application | ELISA, WB, FC, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 27-274 of human TROP-2 (NP_002344.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P09758 | Immunogen Sequence |
Uniprot Id
P09758
Target Species
Human
Target Name
TACSTD2
Target Full Name
Tumor-associated calcium signal transducer 2
Target Function
May function as a growth factor receptor.
Target Involvement
Corneal dystrophy, gelatinous drop-like (GDLD)
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
EPCAM family
Target Tissue Specificity
Placenta, pancreatic carcinoma cell lines.
Target Synonyms
TACSTD2; GA733-1; M1S1; TROP2; Tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1
Target Background
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.
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