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Rabbit anti-Human TROP-2 Polyclonal Antibody

The antibody against TROP-2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-270 of human TROP-2 (NP_002344.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-06828A

The antibody against TROP-2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-270 of human TROP-2 (NP_002344.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

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Specifications


Cat.No ADA-06828A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTROP-2
Target SynonymsEGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; TROP-2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, A-431, BxPC-3ApplicationELISA, WB, IF/ICC, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 27-270 of human TROP-2 (NP_002344.2).Target SpeciesHuman
Uniprot IDP09758Immunogen Sequence
Background Information
  • Uniprot Id

    P09758

  • Target Species

    Human

  • Target Name

    TACSTD2

  • Target Full Name

    Tumor-associated calcium signal transducer 2

  • Target Function

    May function as a growth factor receptor.

  • Target Involvement

    Corneal dystrophy, gelatinous drop-like (GDLD)

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein.

  • Target Protein Families

    EPCAM family

  • Target Tissue Specificity

    Placenta, pancreatic carcinoma cell lines.

  • Target Synonyms

    TACSTD2; GA733-1; M1S1; TROP2; Tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1

  • Target Background

    This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

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