Rabbit anti-Human TRPC7 Polyclonal Antibody

The antibody against TRPC7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 720-780 of human TRPC7 (NP_065122.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07069A

Number

Cat.No	ADA-07069A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	TRPC7
Target Synonyms	TRP7; TRPC7	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T, A-549, Mouse lung, SH-SY5Y, U-251MG, U-87MG	Application	ELISA, WB

Cat.No

ADA-07069A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

TRPC7

Target Synonyms

TRP7; TRPC7

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T, A-549, Mouse lung, SH-SY5Y, U-251MG, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 720-780 of human TRPC7 (NP_065122.1).	Target Species	Human
Immunogen Sequence	YLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRY	Uniprot ID	Q9HCX4

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 720-780 of human TRPC7 (NP_065122.1).

Target Species

Human

Immunogen Sequence

YLIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRY

Uniprot ID

Q9HCX4

Background Information

Uniprot Id

Q9HCX4
Target Species

Human
Target Name

TRPC7
Target Full Name

Short transient receptor potential channel 7
Target Function

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Nucleus envelope.
Target Protein Families

Transient receptor (TC 1.A.4) family, STrpC subfamily, TRPC7 sub-subfamily
Target Synonyms

Capacitative calcium channel TRPC7 ; cation channel; subfamily C; member 7; hTRP7; KNP3 ; Likley ortholog of mouse transient receptor potential cation channel subfamily C member 7; mTRP7; Putative capacitative calcium channel; Short transient receptor potential channel 7; Transient receptor potential cation channel subfamily C member 7; transient receptor potential-related channel 7; a novel putative Ca2+ channel protein ; Transient receptor protein 7; TRP 7; TRP-7; TRP7 protein; TRPC 7; TrpC7; Trpc7 transient receptor potential cation channel; subfamily C; member 7; TRPC7_HUMAN; TRPM2 ; Trrp8
Target Background

Predicted to enable inositol 1, 4, 5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in metal ion transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to act upstream of or within calcium ion transport. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Predicted to be integral component of plasma membrane.

Rabbit anti-Human TRPC7 Polyclonal Antibody

Specifications

Immunogen Information

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