Rabbit anti-Human TRPC7 Polyclonal Antibody

Uniprot Id

Q9HCX4

Target Species

Human

Target Name

TRPC7

Target Full Name

Short transient receptor potential channel 7

Target Function

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion.

Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Nucleus envelope.

Target Protein Families

Transient receptor (TC 1.A.4) family, STrpC subfamily, TRPC7 sub-subfamily

Target Synonyms

Capacitative calcium channel TRPC7 ; cation channel; subfamily C; member 7; hTRP7; KNP3 ; Likley ortholog of mouse transient receptor potential cation channel subfamily C member 7; mTRP7; Putative capacitative calcium channel; Short transient receptor potential channel 7; Transient receptor potential cation channel subfamily C member 7; transient receptor potential-related channel 7; a novel putative Ca2+ channel protein ; Transient receptor protein 7; TRP 7; TRP-7; TRP7 protein; TRPC 7; TrpC7; Trpc7 transient receptor potential cation channel; subfamily C; member 7; TRPC7_HUMAN; TRPM2 ; Trrp8

Target Background

Predicted to enable inositol 1, 4, 5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in metal ion transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to act upstream of or within calcium ion transport. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Predicted to be integral component of plasma membrane.