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Rabbit anti-Human TSPAN15 Polyclonal Antibody

The antibody against TSPAN15 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 110-220 of human TSPAN15 (NP_036471.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05668A

The antibody against TSPAN15 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 110-220 of human TSPAN15 (NP_036471.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-05668A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTSPAN15
Target SynonymsNET7; NET-7; TM4SF15; 2700063A19Rik; TSPAN15FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse spleenApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 110-220 of human TSPAN15 (NP_036471.1).Target SpeciesHuman
Immunogen SequenceGVVALTFRNQTIDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTUniprot IDO95858
Background Information
  • Uniprot Id

    O95858

  • Target Species

    Human

  • Target Name

    TSPAN15

  • Target Full Name

    Tetraspanin-15

  • Target Function

    Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Late endosome membrane.

  • Target Protein Families

    Tetraspanin (TM4SF) family

  • Target Synonyms

    TSPAN15; NET7; TM4SF15; UNQ677/PRO1311; Tetraspanin-15; Tspan-15; Tetraspan NET-7; Transmembrane 4 superfamily member 15

  • Target Background

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene.

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