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The antibody against TSPYL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 240-460 of human TSPYL2 (NP_071400.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TSPYL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 240-460 of human TSPYL2 (NP_071400.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03443A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TSPYL2 |
| Target Synonyms | CDA1; CTCL; NP79; TSPX; CINAP; DENTT; SE204; HRIHFB2216; TSPYL2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat brain, LO2, Mouse brain, Mouse testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 240-460 of human TSPYL2 (NP_071400.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H2G4 | Immunogen Sequence |
Uniprot Id
Q9H2G4
Target Species
Human
Target Name
TSPYL2
Target Full Name
Testis-specific Y-encoded-like protein 2
Target Function
Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
Nucleosome assembly protein (NAP) family
Target Tissue Specificity
Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas.
Target Synonyms
CASK interacting nucleosome assembly protein; CDA1; Cell division autoantigen 1; Cell division autoantigen 1 nucleolar protein; CTCL tumor antigen se20-4; CTCL-associated antigen se20-4; Cutaneous T-cell lymphoma-associated antigen se20-4; DENTT; Differentially-expressed nucleolar TGF-beta1 target protein; HRIHFB2216; NP79; Nuclear protein of 79 kDa; Testis-specific Y-encoded-like protein 2; TSPX; TSPY-like protein 2; TSPYL2; TSYL2_HUMAN
Target Background
This gene encodes a member of the testis-specific protein Y-encoded, TSPY-like/SET/nucleosome assembly protein-1 superfamily. The encoded protein is localized to the nucleolus where it functions in chromatin remodeling and as an inhibitor of cell-cycle progression. This protein may play a role in the suppression of tumor growth.
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