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The antibody against TSSK4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 79-328 of human TSSK4 (NP_777604.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TSSK4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 79-328 of human TSSK4 (NP_777604.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10972A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TSSK4 |
| Target Synonyms | TSK4; TSK-4; TSSK5; STK22E; C14orf20; TSSK4 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 79-328 of human TSSK4 (NP_777604.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6SA08 | Immunogen Sequence |
Uniprot Id
Q6SA08
Target Species
Human
Target Name
TSSK4
Target Full Name
Testis-specific serine/threonine-protein kinase 4
Target Function
Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. Phosphorylates ODF2 on 'Ser-95'.
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum.
Target Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family
Target Tissue Specificity
Expressed only in the testis.
Target Synonyms
C14orf20; Serine/threonine-protein kinase 22E; STK22E; Testis-specific kinase 4; Testis-specific serine/threonine-protein kinase 4; TSK-4; TSSK-4; Tssk4; TSSK4_HUMAN; TSSK5
Target Background
This gene encodes a member of the testis-specific serine/threonine kinase family. The encoded protein is thought to be involved in spermatogenesis via stimulation of the CREB/CRE responsive pathway through phosphorylation of the cAMP responsive element binding protein transcription factor. Alternative splicing results in multiple transcript variants.
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