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Rabbit anti-Human TST Polyclonal Antibody

The antibody against TST was raised in rabbit using the Recombinant Human Thiosulfate sulfurtransferase protein (2-297AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

ADC-05721A

The antibody against TST was raised in rabbit using the Recombinant Human Thiosulfate sulfurtransferase protein (2-297AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-05721A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTST
Target SynonymsGlpE antibody; RDS antibody; Rhodanese antibody; Thiosulfate sulfurtransferase antibody; Thiosulfate sulfurtransferase GlpE antibody; THTR_HUMAN antibody; TST antibodyFormLiquid
Species ReactivityHuman, RatIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Thiosulfate sulfurtransferase protein (2-297AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ16762
Background Information
  • Uniprot Id

    Q16762

  • Target Species

    Human

  • Target Name

    TST

  • Target Full Name

    Thiosulfate sulfurtransferase

  • Target Function

    Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity. Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA.

  • Target Subcellular Location

    Mitochondrion matrix.

  • Target Synonyms

    GlpE; RDS; Rhodanese; Thiosulfate sulfurtransferase; Thiosulfate sulfurtransferase GlpE; THTR_HUMAN; TST

  • Target Background

    This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants.

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