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The antibody against TTF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human TTF2 (NP_003585.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against TTF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human TTF2 (NP_003585.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-01965A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TTF2 |
| Target Synonyms | F2; HuF2; ZGRF6; TTF2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HL-60, Jurkat, MCF7, SKOV3 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human TTF2 (NP_003585.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UNY4 | Immunogen Sequence |
Uniprot Id
Q9UNY4
Target Species
Human
Target Name
TTF2
Target Full Name
Transcription termination factor 2
Target Function
DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis.
Target Protein Families
SNF2/RAD54 helicase family
Target Synonyms
F2; Factor 2; Factor2; HuF 2; HuF2; Human factor 2; Lodestar homolog; Lodestar protein; RNA polymerase II termination factor; Transcription release factor 2; Transcription termination factor 2; Transcription termination factor RNA polymerase II; TTF2; TTF2_HUMAN
Target Background
This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.
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