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The antibody against TXN2 was raised in rabbit using the Recombinant Human Thioredoxin, mitochondrial protein (1-166AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against TXN2 was raised in rabbit using the Recombinant Human Thioredoxin, mitochondrial protein (1-166AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human tonsil tissue using TXN2 Antibody at dilution of 1:1002
| Cat.No | ADC-44458A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TXN2 |
| Target Synonyms | TXN2 antibody; TRX2 antibody; Thioredoxin antibody; mitochondrial antibody; MTRX antibody; Mt-Trx antibody; Thioredoxin-2 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Thioredoxin, mitochondrial protein (1-166AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99757 |
Uniprot Id
Q99757
Target Species
Human
Target Name
TXN2
Target Full Name
Thioredoxin, mitochondrial
Target Function
Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.
Target Involvement
Combined oxidative phosphorylation deficiency 29 (COXPD29)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Thioredoxin family
Target Tissue Specificity
Widely expressed in adult (at protein level) and fetal tissues.
Target Research Area
Signal Transduction
Target Synonyms
TXN2; TRX2; Thioredoxin; mitochondrial; MTRX; Mt-Trx; Thioredoxin-2
Target Background
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
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