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The antibody against TYRP1 was raised in rabbit using the Recombinant Human 5,6-dihydroxyindole-2-carboxylic acid oxidase protein (91-186AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against TYRP1 was raised in rabbit using the Recombinant Human 5,6-dihydroxyindole-2-carboxylic acid oxidase protein (91-186AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-02138A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TYRP1 |
| Target Synonyms | 6-dihydroxyindole-2-carboxylic acid oxidase; DHICA oxidase; Catalase B; Glycoprotein 75; Melanoma antigen gp75; Tyrosinase-related protein 1; TRP; TRP-1; TRP1, TYRP1; CAS2; TYRP; TYRRP; 5 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human 5,6-dihydroxyindole-2-carboxylic acid oxidase protein (91-186AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P17643 |
Uniprot Id
P17643
Target Species
Human
Target Name
TYRP1
Target Full Name
5,6-dihydroxyindole-2-carboxylic acid oxidase
Target Function
Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.
Target Involvement
Albinism, oculocutaneous, 3 (OCA3)
Target Subcellular Location
Melanosome membrane; Single-pass type I membrane protein. Melanosome.
Target Protein Families
Tyrosinase family
Target Tissue Specificity
Pigment cells.
Target Synonyms
TYRP1; CAS2; TYRP; TYRRP; 5,6-dihydroxyindole-2-carboxylic acid oxidase; DHICA oxidase; Catalase B; Glycoprotein 75; Melanoma antigen gp75; Tyrosinase-related protein 1; TRP; TRP-1; TRP1
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