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The antibody against UBAC2 was raised in rabbit using the Recombinant Human Ubiquitin-associated domain-containing protein 2 protein (1-157AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against UBAC2 was raised in rabbit using the Recombinant Human Ubiquitin-associated domain-containing protein 2 protein (1-157AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-04672A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UBAC2 |
| Target Synonyms | UBAC2; PHGDHL1; PSEC0110; Ubiquitin-associated domain-containing protein 2; UBA domain-containing protein 2; Phosphoglycerate dehydrogenase-like protein 1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ubiquitin-associated domain-containing protein 2 protein (1-157AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8NBM4 |
Uniprot Id
Q8NBM4
Target Species
Human
Target Name
UBAC2
Target Full Name
Ubiquitin-associated domain-containing protein 2
Target Function
Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets. In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Synonyms
UBAC2; PHGDHL1; PSEC0110; Ubiquitin-associated domain-containing protein 2; UBA domain-containing protein 2; Phosphoglycerate dehydrogenase-like protein 1
Target Background
Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of retrograde protein transport, ER to cytosol. Acts upstream of or within protein localization to endoplasmic reticulum. Located in endoplasmic reticulum.
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