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The antibody against UBE3C was raised in rabbit using the Synthesized peptide derived from the Internal region of Human UBE3C. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against UBE3C was raised in rabbit using the Synthesized peptide derived from the Internal region of Human UBE3C. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of HuvEc cells using UBE3C Polyclonal Antibody
Western Blot analysis of K562 cells using UBE3C Polyclonal Antibody2
| Cat.No | ADC-37405A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UBE3C |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human UBE3C. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15386 |
Uniprot Id
Q15386
Target Species
Human
Target Name
UBE3C
Target Full Name
Ubiquitin-protein ligase E3C
Target Function
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.
Target Synonyms
HectH2; KIAA0010; KIAA10; Ube3c; UBE3C_HUMAN; Ubiquitin protein isopeptide ligase (E3); Ubiquitin protein ligase E3C; Ubiquitin-protein ligase E3C
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