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Rabbit anti-Human UBLCP1 Polyclonal Antibody

The antibody against UBLCP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 99-318 of human UBLCP1 (NP_659486.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06079A

The antibody against UBLCP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 99-318 of human UBLCP1 (NP_659486.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-06079A ClonalityPolyclonal
Host SpeciesRabbitTarget NameUBLCP1
Target SynonymsCPUB1; UBLCP1FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, 293T, A-549, Mouse brain, OVCAR3, SGC-7901ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 99-318 of human UBLCP1 (NP_659486.2).Target SpeciesHuman
Uniprot IDQ8WVY7Immunogen Sequence
Background Information
  • Uniprot Id

    Q8WVY7

  • Target Species

    Human

  • Target Name

    UBLCP1

  • Target Full Name

    Ubiquitin-like domain-containing CTD phosphatase 1

  • Target Function

    Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.

  • Target Subcellular Location

    Nucleus. Note=Colocalizes with nuclear proteasomes.

  • Target Tissue Specificity

    Broadly expressed, with highest levels in placenta, lung, testis and ovary. Up-regulated in tumor tissues.

  • Target Synonyms

    CPUB1; CTD like phosphatase domain containing protein; CTD phosphatase like with ubiquitin domain 1; FLJ25267; MGC10067; Nuclear proteasome inhibitor UBLCP1; UBCP1_HUMAN; Ubiquitin like domain containing CTD phosphatase 1; Ubiquitin-like domain-containing CTD phosphatase 1; UBLCP1

  • Target Background

    Enables protein serine/threonine phosphatase activity. Involved in protein dephosphorylation. Located in nucleolus and nucleoplasm.

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