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Rabbit anti-Human UBXN6 Polyclonal Antibody

The antibody against UBXN6 was raised in rabbit using the Human UBXN6 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-46785A

The antibody against UBXN6 was raised in rabbit using the Human UBXN6 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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Specifications


Cat.No ADC-46785A ClonalityPolyclonal
Host SpeciesRabbitTarget NameUBXN6
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman UBXN6Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9BZV1
Background Information
  • Uniprot Id

    Q9BZV1

  • Target Species

    Human

  • Target Name

    UBXN6

  • Target Full Name

    UBX domain-containing protein 6

  • Target Function

    May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes. As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Early endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein.

  • Target Tissue Specificity

    Enhanced expression in testis.

  • Target Synonyms

    UBX domain containing 1; UBX domain containing 2; UBX domain containing protein 1; UBX domain containing protein 6; UBX domain protein 6; UBX domain-containing protein 1; UBX domain-containing protein 6; UBXD1; UBXDC2; Ubxn6; UBXN6_HUMAN

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