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Rabbit anti-Human UCKL1 Polyclonal Antibody

The antibody against UCKL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human UCKL1 (NP_060329.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-00579A

The antibody against UCKL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human UCKL1 (NP_060329.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-00579A ClonalityPolyclonal
Host SpeciesRabbitTarget NameUCKL1
Target SynonymsUCK1L; URKL1; UCKL1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, Mouse lung, Rat pancreasApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human UCKL1 (NP_060329.2).Target SpeciesHuman
Immunogen SequenceMAAPPARADADPSPTSPPTARDTPGRQAEKSETACEDRSNAESLDRLLPPVGTGRSPRKRTTSQCKSEPPLLRTSKRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSFYKVLTEQQQEQAAHNNFNFDHPDAFDFDLIISTLKKLKQGKSVKVPIYDFTTHSRKKDWKTLYGAUniprot IDQ9NWZ5
Background Information
  • Uniprot Id

    Q9NWZ5

  • Target Species

    Human

  • Target Name

    UCKL1

  • Target Full Name

    Uridine-cytidine kinase-like 1

  • Target Function

    May contribute to UTP accumulation needed for blast transformation and proliferation.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Note=EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.

  • Target Protein Families

    Uridine kinase family

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    F538; UCK 1L; UCK1 like; UCK1L; UCKL 1; UCKL1; UCKL1_HUMAN; Uridine cytidine kinase 1 like 1; Uridine kinase like 1; Uridine-cytidine kinase-like 1; Uridine/cytidine kinase like 1; URKL 1; URKL1

  • Target Background

    The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants.

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