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The antibody against UCKL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human UCKL1 (NP_060329.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against UCKL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human UCKL1 (NP_060329.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-00579A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UCKL1 |
| Target Synonyms | UCK1L; URKL1; UCKL1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse lung, Rat pancreas | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human UCKL1 (NP_060329.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MAAPPARADADPSPTSPPTARDTPGRQAEKSETACEDRSNAESLDRLLPPVGTGRSPRKRTTSQCKSEPPLLRTSKRTIYTAGRPPWYNEHGTQSKEAFAIGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSFYKVLTEQQQEQAAHNNFNFDHPDAFDFDLIISTLKKLKQGKSVKVPIYDFTTHSRKKDWKTLYGA | Uniprot ID | Q9NWZ5 |
Uniprot Id
Q9NWZ5
Target Species
Human
Target Name
UCKL1
Target Full Name
Uridine-cytidine kinase-like 1
Target Function
May contribute to UTP accumulation needed for blast transformation and proliferation.
Target Subcellular Location
Cytoplasm. Nucleus. Note=EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.
Target Protein Families
Uridine kinase family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
F538; UCK 1L; UCK1 like; UCK1L; UCKL 1; UCKL1; UCKL1_HUMAN; Uridine cytidine kinase 1 like 1; Uridine kinase like 1; Uridine-cytidine kinase-like 1; Uridine/cytidine kinase like 1; URKL 1; URKL1
Target Background
The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants.
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