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The antibody against UGT2B4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human UGT2B4 (NP_066962.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against UGT2B4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human UGT2B4 (NP_066962.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03998A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UGT2B4 |
| Target Synonyms | HLUG25; UDPGTH1; UGT2B11; UDPGT2B4; UDPGTh-1; UGT2B4 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, 22Rv1, B cells, HT-1080, Mouse brain, Mouse liver, Rat kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human UGT2B4 (NP_066962.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P06133 | Immunogen Sequence |
Uniprot Id
P06133
Target Species
Human
Target Name
UGT2B4
Target Full Name
UDP-glucuronosyltransferase 2B4
Target Function
UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of the endogenous estrogen hormones such as estradiol and estriol.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Protein Families
UDP-glycosyltransferase family
Target Synonyms
UGT2B4; UGT2B11; UDP-glucuronosyltransferase 2B4; UDPGT 2B4; EC 2.4.1.17; HLUG25; Hyodeoxycholic acid-specific UDPGT; UDPGTh-1
Target Background
Enables glucuronosyltransferase activity. Involved in cellular glucuronidation and estrogen metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle.
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