Rabbit anti-Human ULBP1 Polyclonal Antibody

The antibody against ULBP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 26-216 of human ULBP1 (NP_079494.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-01560A

Number

Cat.No	ADA-01560A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ULBP1
Target Synonyms	N2DL-1; RAET1I; NKG2DL1; ULBP1	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Raji	Application	ELISA, WB, IHC-P

Cat.No

ADA-01560A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ULBP1

Target Synonyms

N2DL-1; RAET1I; NKG2DL1; ULBP1

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Raji

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 26-216 of human ULBP1 (NP_079494.1).	Target Species	Human
Immunogen Sequence	GWVDTHCLCYDFIITPKSRPEPQWCEVQGLVDERPFLHYDCVNHKAKAFASLGKKVNVTKTWEEQTETLRDVVDFLKGQLLDIQVENLIPIEPLTLQARMSCEHEAHGHGRGSWQFLFNGQKFLLFDSNNRKWTALHPGAKKMTEKWEKNRDVTMFFQKISLGDCKMWLEEFLMYWEQMLDPTKPPSLAPG	Uniprot ID	Q9BZM6

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 26-216 of human ULBP1 (NP_079494.1).

Target Species

Human

Immunogen Sequence

GWVDTHCLCYDFIITPKSRPEPQWCEVQGLVDERPFLHYDCVNHKAKAFASLGKKVNVTKTWEEQTETLRDVVDFLKGQLLDIQVENLIPIEPLTLQARMSCEHEAHGHGRGSWQFLFNGQKFLLFDSNNRKWTALHPGAKKMTEKWEKNRDVTMFFQKISLGDCKMWLEEFLMYWEQMLDPTKPPSLAPG

Uniprot ID

Q9BZM6

Background Information

Uniprot Id

Q9BZM6
Target Species

Human
Target Name

ULBP1
Target Full Name

UL16-binding protein 1
Target Function

Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Target Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum.
Target Protein Families

MHC class I family
Target Tissue Specificity

Expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues including heart, brain, lung, liver, testis, lymph node, thymus, tonsil and bone marrow. Also found in fetal heart, brain, lung and liver.
Target Synonyms

Alcan beta; ALCAN-beta; N2DL-1; N2DL1; N2DL1_HUMAN; NKG2D ligand 1; NKG2D ligand 1 precursor; NKG2DL1; RAET1I; Retinoic acid early transcript 1I; UL16; UL16 binding protein 1; UL16-binding protein 1; ULBP1
Target Background

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human ULBP1 Polyclonal Antibody

Specifications

Immunogen Information

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