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The antibody against UROS was raised in rabbit using the Recombinant Human Uroporphyrinogen-III synthase protein (1-265AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against UROS was raised in rabbit using the Recombinant Human Uroporphyrinogen-III synthase protein (1-265AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-21133A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UROS |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Uroporphyrinogen-III synthase protein (1-265AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P10746 |
Uniprot Id
P10746
Target Species
Human
Target Name
UROS
Target Full Name
Uroporphyrinogen-III synthase
Target Function
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).
Target Involvement
Congenital erythropoietic porphyria (CEP)
Target Protein Families
Uroporphyrinogen-III synthase family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
congenital erythropoietic porphyria; HEM4_HUMAN; Hydroxymethylbilane hydrolyase [cyclizing]; Hydroxymethylbilane hydrolyase; OTTHUMP00000020709; OTTHUMP00000020710; UROIIIS; Uroporphyrinogen III cosynthetase; Uroporphyrinogen III synthase (congenital erythropoietic porphyria); Uroporphyrinogen III synthase; Uroporphyrinogen-III cosynthase; Uroporphyrinogen-III synthase; UROS
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