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The antibody against UROS was raised in rabbit using the Human UROS as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against UROS was raised in rabbit using the Human UROS as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-46762A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UROS |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human UROS | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P10746 |
Uniprot Id
P10746
Target Species
Human
Target Name
UROS
Target Full Name
Uroporphyrinogen-III synthase
Target Function
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).
Target Involvement
Congenital erythropoietic porphyria (CEP)
Target Protein Families
Uroporphyrinogen-III synthase family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
congenital erythropoietic porphyria; HEM4_HUMAN; Hydroxymethylbilane hydrolyase [cyclizing]; Hydroxymethylbilane hydrolyase; OTTHUMP00000020709; OTTHUMP00000020710; UROIIIS; Uroporphyrinogen III cosynthetase; Uroporphyrinogen III synthase (congenital erythropoietic porphyria); Uroporphyrinogen III synthase; Uroporphyrinogen-III cosynthase; Uroporphyrinogen-III synthase; UROS
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