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The antibody against USP34 was raised in rabbit using the Human USP34 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against USP34 was raised in rabbit using the Human USP34 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-51402A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | USP34 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human USP34 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q70CQ2 |
Uniprot Id
Q70CQ2
Target Species
Human
Target Name
USP34
Target Full Name
Ubiquitin carboxyl-terminal hydrolase 34
Target Function
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Target Protein Families
Peptidase C19 family
Target Tissue Specificity
Expressed in brain at low level.
Target Synonyms
Deubiquitinating enzyme 34; FLJ43910; KIAA0570; KIAA0729; MGC104459; Ubiquitin carboxyl terminal hydrolase 34; Ubiquitin carboxyl-terminal hydrolase 34; Ubiquitin specific processing protease 34; Ubiquitin specific protease 34; Ubiquitin thioesterase 34; Ubiquitin thiolesterase 34; Ubiquitin-specific-processing protease 34; UBP34_HUMAN; USP 34; Usp34
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