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The antibody against USP45 was raised in rabbit using the Synthesized peptide derived from internal of Human USP45. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against USP45 was raised in rabbit using the Synthesized peptide derived from internal of Human USP45. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from A549 cells, using USP45 antibody.
| Cat.No | ADC-40835A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | USP45 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human USP45. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q70EL2 |
Uniprot Id
Q70EL2
Target Species
Human
Target Name
USP45
Target Full Name
Ubiquitin carboxyl-terminal hydrolase 45
Target Function
Catalyzes the deubiquitination of SPDL1. Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites. May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development. Plays a role in cell migration.
Target Subcellular Location
Photoreceptor inner segment. Cytoplasm. Nucleus.
Target Protein Families
Peptidase C19 family
Target Tissue Specificity
Widely expressed. High expression is detected in the cerebellum. In the eye, it is expressed at high levels in the optic nerve, sclera and retina, with relatively low levels in the choroid, lens and retinal pigment epithelium.
Target Synonyms
USP45; Ubiquitin carboxyl-terminal hydrolase 45; EC 3.4.19.12; Deubiquitinating enzyme 45; Ubiquitin thioesterase 45; Ubiquitin-specific-processing protease 45
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