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The antibody against USP49 was raised in rabbit using the Human USP49 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against USP49 was raised in rabbit using the Human USP49 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-46747A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | USP49 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human USP49 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q70CQ1 |
Uniprot Id
Q70CQ1
Target Species
Human
Target Name
USP49
Target Full Name
Ubiquitin carboxyl-terminal hydrolase 49
Target Function
Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
Target Subcellular Location
Nucleus.
Target Protein Families
Peptidase C19 family
Target Synonyms
USP49; Ubiquitin carboxyl-terminal hydrolase 49; EC 3.4.19.12; Deubiquitinating enzyme 49; Ubiquitin thioesterase 49; Ubiquitin-specific-processing protease 49
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