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The antibody against USP53 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human USP53. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against USP53 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human USP53. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-34628A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | USP53 |
| Target Synonyms | USP53 antibody; KIAA1350 antibody; Inactive ubiquitin carboxyl-terminal hydrolase 53 antibody; Inactive ubiquitin-specific peptidase 53 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human USP53. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q70EK8 |
Uniprot Id
Q70EK8
Target Species
Human
Target Name
USP53
Target Full Name
Inactive ubiquitin carboxyl-terminal hydrolase 53
Target Function
Tight junction-associated protein that is involved in the survival of auditory hair cells and hearing. Maybe by modulating the barrier properties and mechanical stability of tight junctions. Has no peptidase activity.
Target Subcellular Location
Cell junction, tight junction.
Target Protein Families
Peptidase C19 family
Target Tissue Specificity
Expressed predominantly in skeletal muscle and heart.
Target Synonyms
USP53; KIAA1350; Inactive ubiquitin carboxyl-terminal hydrolase 53; Inactive ubiquitin-specific peptidase 53
Target Background
Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in response to auditory stimulus and sensory perception of sound. Predicted to act upstream of or within action potential and neuron apoptotic process. Predicted to be located in bicellular tight junction. Predicted to be active in cell-cell junction.
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