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The antibody against VAMP1 was raised in rabbit using the Recombinant Human Vesicle-associated membrane protein 1 protein (1-96AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against VAMP1 was raised in rabbit using the Recombinant Human Vesicle-associated membrane protein 1 protein (1-96AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human liver cancer using VAMP1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using VAMP1 Antibody at dilution of 1:1002
| Cat.No | ADC-21126A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VAMP1 |
| Target Synonyms | VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Vesicle-associated membrane protein 1 protein (1-96AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P23763 |
Uniprot Id
P23763
Target Species
Human
Target Name
VAMP1
Target Full Name
Vesicle-associated membrane protein 1
Target Function
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
Target Involvement
Spastic ataxia 1, autosomal dominant (SPAX1)
Target Subcellular Location
[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.; [Isoform 2]: Cytoplasmic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.; [Isoform 3]: Mitochondrion outer membrane; Single-pass type IV membrane protein.
Target Protein Families
Synaptobrevin family
Target Tissue Specificity
Nervous system, skeletal muscle and adipose tissue.
Target Synonyms
VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1
Target Background
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.
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