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Rabbit anti-Human VAMP1 Polyclonal Antibody

The antibody against VAMP1 was raised in rabbit using the Human VAMP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-51390A

The antibody against VAMP1 was raised in rabbit using the Human VAMP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-51390A ClonalityPolyclonal
Host SpeciesRabbitTarget NameVAMP1
Target SynonymsVAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman VAMP1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP23763
Background Information
  • Uniprot Id

    P23763

  • Target Species

    Human

  • Target Name

    VAMP1

  • Target Full Name

    Vesicle-associated membrane protein 1

  • Target Function

    Involved in the targeting and/or fusion of transport vesicles to their target membrane.

  • Target Involvement

    Spastic ataxia 1, autosomal dominant (SPAX1)

  • Target Subcellular Location

    [Isoform 1]: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.; [Isoform 2]: Cytoplasmic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.; [Isoform 3]: Mitochondrion outer membrane; Single-pass type IV membrane protein.

  • Target Protein Families

    Synaptobrevin family

  • Target Tissue Specificity

    Nervous system, skeletal muscle and adipose tissue.

  • Target Synonyms

    VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1

  • Target Background

    Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.

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