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Rabbit anti-Human VAMP3/Cellubrevin Polyclonal Antibody

The antibody against VAMP3/Cellubrevin was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human VAMP3/Cellubrevin (NP_004772.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02497A

The antibody against VAMP3/Cellubrevin was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human VAMP3/Cellubrevin (NP_004772.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-02497A ClonalityPolyclonal
Host SpeciesRabbitTarget NameVAMP3/Cellubrevin
Target SynonymsCEB; VAMP3/CellubrevinFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, Rat brain, 293T, A-549, Mouse lung, Mouse testis, SKOV3, SW480, U-251MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human VAMP3/Cellubrevin (NP_004772.1).Target SpeciesHuman
Immunogen SequenceMSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAUniprot IDQ15836
Background Information
  • Uniprot Id

    Q15836

  • Target Species

    Human

  • Target Name

    VAMP3

  • Target Full Name

    Vesicle-associated membrane protein 3

  • Target Function

    SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.

  • Target Subcellular Location

    Membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.

  • Target Protein Families

    Synaptobrevin family

  • Target Synonyms

    CEB; Cellubrevin; Synaptobrevin 3; Synaptobrevin-3; VAMP 3; VAMP-3; VAMP3; VAMP3_HUMAN; Vesicle associated membrane protein 3; Vesicle-associated membrane protein 3

  • Target Background

    Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.

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