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The antibody against VARS2 was raised in rabbit using the Recombinant Human Valine--tRNA ligase, mitochondrial protein (830-981AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against VARS2 was raised in rabbit using the Recombinant Human Valine–tRNA ligase, mitochondrial protein (830-981AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-04044A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VARS2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Valine--tRNA ligase, mitochondrial protein (830-981AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5ST30 |
Uniprot Id
Q5ST30
Target Species
Human
Target Name
VARS2
Target Full Name
Valine--tRNA ligase, mitochondrial
Target Involvement
Combined oxidative phosphorylation deficiency 20 (COXPD20)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Synonyms
COXPD20; mitochondrial; SYVM_HUMAN; Valine--tRNA ligase; ValRS; Valyl tRNA synthetase 2 mitochondrial; Valyl-tRNA synthetase; Valyl-tRNA synthetase-like; Vars2; VARS2L; VARSL
Target Background
This gene encodes a mitochondrial aminoacyl-tRNA synthetase, which catalyzes the attachment of valine to tRNA(Val) for mitochondrial translation. Mutations in this gene cause combined oxidative phosphorylation deficiency-20, and are also associated with early-onset mitochondrial encephalopathies. Alternative splicing of this gene results in multiple transcript variants.
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