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The antibody against VARS2 was raised in rabbit using the Human VARS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against VARS2 was raised in rabbit using the Human VARS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-46736A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VARS2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human VARS2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5ST30 |
Uniprot Id
Q5ST30
Target Species
Human
Target Name
VARS2
Target Full Name
Valine--tRNA ligase, mitochondrial
Target Involvement
Combined oxidative phosphorylation deficiency 20 (COXPD20)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Synonyms
COXPD20; mitochondrial; SYVM_HUMAN; Valine--tRNA ligase; ValRS; Valyl tRNA synthetase 2 mitochondrial; Valyl-tRNA synthetase; Valyl-tRNA synthetase-like; Vars2; VARS2L; VARSL
Target Background
This gene encodes a mitochondrial aminoacyl-tRNA synthetase, which catalyzes the attachment of valine to tRNA(Val) for mitochondrial translation. Mutations in this gene cause combined oxidative phosphorylation deficiency-20, and are also associated with early-onset mitochondrial encephalopathies. Alternative splicing of this gene results in multiple transcript variants.
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