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Rabbit anti-Human VIP Polyclonal Antibody

The antibody against VIP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human VIP (NP_003372.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-02544A

The antibody against VIP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human VIP (NP_003372.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-02544A ClonalityPolyclonal
Host SpeciesRabbitTarget NameVIP
Target SynonymsPHM27; VIPFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesRat spinal cordApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 31-170 of human VIP (NP_003372.1).Target SpeciesHuman
Immunogen SequenceAPSALRLGDRIPFEGANEPDQVSLKEDIDMLQNALAENDTPYYDVSRNARHADGVFTSDFSKLLGQLSAKKYLESLMGKRVSSNISEDPVPVKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSEGESPDFPEELEKUniprot IDP01282
Background Information
  • Uniprot Id

    P01282

  • Target Species

    Human

  • Target Name

    VIP

  • Target Full Name

    VIP peptides

  • Target Function

    VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.; PHM and PHV also cause vasodilation. PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Glucagon family

  • Target Synonyms

    Peptide histidine methioninamide 27; Peptide histidine valine 42; PHM27; PHV42; Prepro VIP; Vasoactive intestinal peptide; Vasoactive intestinal polypeptide; VIP; VIP peptides; VIP peptides precursor; VIP_HUMAN

  • Target Background

    The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

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