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The antibody against WDFY4 was raised in rabbit using the Recombinant Human WD repeat- and FYVE domain-containing protein 4 protein (1-322AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against WDFY4 was raised in rabbit using the Recombinant Human WD repeat- and FYVE domain-containing protein 4 protein (1-322AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human prostate cancer using WDFY4 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human appendix tissue using WDFY4 Antibody at dilution of 1:1002
| Cat.No | ADC-15325A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | WDFY4 |
| Target Synonyms | WDFY4 antibody; C10orf64 antibody; KIAA1607WD repeat- and FYVE domain-containing protein 4 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human WD repeat- and FYVE domain-containing protein 4 protein (1-322AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6ZS81 |
Uniprot Id
Q6ZS81
Target Species
Human
Target Name
WDFY4
Target Full Name
WD repeat- and FYVE domain-containing protein 4
Target Function
Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.
Target Subcellular Location
Early endosome. Endoplasmic reticulum.
Target Synonyms
WDFY4; C10orf64; KIAA1607WD repeat- and FYVE domain-containing protein 4
Target Background
Predicted to be involved in autophagy. Predicted to act upstream of or within with a positive effect on CD8-positive, alpha-beta T cell activation. Predicted to act upstream of or within antigen processing and presentation and cellular response to virus. Predicted to be located in early endosome and endoplasmic reticulum.
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