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The antibody against WDR24 was raised in rabbit using the Recombinant Human GATOR complex protein WDR24 protein (1-298AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against WDR24 was raised in rabbit using the Recombinant Human GATOR complex protein WDR24 protein (1-298AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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| Cat.No | ADC-01819A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | WDR24 |
| Target Synonyms | C16orf21 antibody; DKFZp434F054 antibody; JFP7 antibody; LA16c-313D11.2 antibody; WD repeat-containing protein 24 antibody; wdr24 antibody; WDR24_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human GATOR complex protein WDR24 protein (1-298AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96S15 |
Uniprot Id
Q96S15
Target Species
Human
Target Name
WDR24
Target Full Name
GATOR2 complex protein WDR24
Target Function
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux.
Target Subcellular Location
Lysosome membrane.
Target Protein Families
WD repeat WDR24 family
Target Synonyms
C16orf21; DKFZp434F054; JFP7; LA16c-313D11.2; WD repeat-containing protein 24; wdr24; WDR24_HUMAN
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