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The antibody against WDR46 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 421-610 of human WDR46 (NP_005443.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against WDR46 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 421-610 of human WDR46 (NP_005443.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using WDR46 Rabbit pAb at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
| Cat.No | ADA-00513A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | WDR46 |
| Target Synonyms | UTP7; BING4; FP221; C6orf11; WDR46 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 421-610 of human WDR46 (NP_005443.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | DVVNIWAGQGKASPPSLEQPYLTHRLSGPVHGLQFCPFEDVLGVGHTGGITSMLVPGAGEPNFDGLESNPYRSRKQRQEWEVKALLEKVPAELICLDPRALAEVDVISLEQGKKEQIERLGYDPQAKAPFQPKPKQKGRSSTASLVKRKRKVMDEEHRDKVRQSLQQQHHKEAKAKPTGARPSALDRFVR | Uniprot ID | O15213 |
Uniprot Id
O15213
Target Species
Human
Target Name
WDR46
Target Full Name
WD repeat-containing protein 46
Target Function
Scaffold component of the nucleolar structure. Required for localization of DDX21 and NCL to the granular compartment of the nucleolus.
Target Subcellular Location
Nucleus, nucleolus.
Target Synonyms
WDR46; BING4; C6orf11; FP221; WD repeat-containing protein 46; WD repeat-containing protein BING4
Target Background
Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus.
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