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The antibody against WDR62 was raised in rabbit using the Recombinant Human WD repeat-containing protein 62 protein (889-1188AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against WDR62 was raised in rabbit using the Recombinant Human WD repeat-containing protein 62 protein (889-1188AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human bladder cancer using WDR62 Antibody at dilution of 1:100
| Cat.No | ADC-21107A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | WDR62 |
| Target Synonyms | WDR62 antibody; C19orf14 antibody; WD repeat-containing protein 62 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human WD repeat-containing protein 62 protein (889-1188AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43379 |
Uniprot Id
O43379
Target Species
Human
Target Name
WDR62
Target Full Name
WD repeat-containing protein 62
Target Function
Required for cerebral cortical development. Plays a role in neuronal proliferation and migration. Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication.
Target Involvement
Microcephaly 2, primary, autosomal recessive, with or without cortical malformations (MCPH2)
Target Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Target Tissue Specificity
Present in fetal brain, enriched within the ventricular and subventricular zone (at protein level). In the embryonic brain it is expressed in mitotic neural precursor cells.
Target Synonyms
WDR62; C19orf14; WD repeat-containing protein 62
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