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The antibody against WDR91 was raised in rabbit using the Synthetic peptide of Human WDR91 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against WDR91 was raised in rabbit using the Synthetic peptide of Human WDR91 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-25507A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | WDR91 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human WDR91 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A4D1P6 |
Uniprot Id
A4D1P6
Target Species
Human
Target Name
WDR91
Target Full Name
WD repeat-containing protein 91
Target Function
Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis.
Target Subcellular Location
Early endosome membrane; Peripheral membrane protein. Late endosome membrane.
Target Protein Families
WD repeat WDR91 family
Target Synonyms
HSPC049; WD repeat containing protein 91; WD repeat domain 91; WD repeat-containing protein 91; WDR 91; WDR91; WDR91_HUMAN
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