Rabbit anti-Human WLS Polyclonal Antibody

The antibody against WLS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 43-232 of human WLS (NP_001002292.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07240A

Number

Cat.No	ADA-07240A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	WLS
Target Synonyms	EVI; MRP; ZKS; GPR177; mig-14; C1orf139; WLS	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, Mouse brain, Mouse lung, Rat kidney, SH-SY5Y	Application	ELISA, WB

Cat.No

ADA-07240A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

WLS

Target Synonyms

EVI; MRP; ZKS; GPR177; mig-14; C1orf139; WLS

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, Mouse brain, Mouse lung, Rat kidney, SH-SY5Y

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 43-232 of human WLS (NP_001002292.3).	Target Species	Human
Immunogen Sequence	YMSVKCVDARKNHHKTKWFVPWGPNHCDKIRDIEEAIPREIEANDIVFSVHIPLPHMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDAFAEWTEMAHERVPRKLKCTFTSPKTPEHEGRYYECDVLPFMEIGSVAHKFYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVW	Uniprot ID	Q5T9L3

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 43-232 of human WLS (NP_001002292.3).

Target Species

Human

Immunogen Sequence

YMSVKCVDARKNHHKTKWFVPWGPNHCDKIRDIEEAIPREIEANDIVFSVHIPLPHMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDAFAEWTEMAHERVPRKLKCTFTSPKTPEHEGRYYECDVLPFMEIGSVAHKFYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVW

Uniprot ID

Q5T9L3

Background Information

Uniprot Id

Q5T9L3
Target Species

Human
Target Name

WLS
Target Full Name

Protein wntless homolog
Target Function

Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development.
Target Subcellular Location

Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Target Protein Families

Wntless family
Target Synonyms

WLS; C1orf139; GPR177; UNQ85/PRO18667; Protein wntless homolog; Integral membrane protein GPR177; Protein evenness interrupted homolog; EVI; Putative NF-kappa-B-activating protein 373
Target Background

Enables Wnt-protein binding activity and identical protein binding activity. Involved in positive regulation of cell communication and protein transport. Located in several cellular components, including Golgi apparatus; early endosome; and endoplasmic reticulum membrane.

Rabbit anti-Human WLS Polyclonal Antibody

Specifications

Immunogen Information

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