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Rabbit anti-Human WSB1 Polyclonal Antibody

The antibody against WSB1 was raised in rabbit using the Human WSB1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-51338A

The antibody against WSB1 was raised in rabbit using the Human WSB1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-51338A ClonalityPolyclonal
Host SpeciesRabbitTarget NameWSB1
Target SynonymsWSB1 antibody; SWIP1 antibody; WD repeat and SOCS box-containing protein 1 antibody; WSB-1 antibody; SOCS box-containing WD protein SWiP-1 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman WSB1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y6I7
Background Information
  • Uniprot Id

    Q9Y6I7

  • Target Species

    Human

  • Target Name

    WSB1

  • Target Full Name

    WD repeat and SOCS box-containing protein 1

  • Target Function

    Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.

  • Target Synonyms

    WSB1; SWIP1; WD repeat and SOCS box-containing protein 1; WSB-1; SOCS box-containing WD protein SWiP-1

  • Target Background

    This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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