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The antibody against XYLT1 was raised in rabbit using the Human XYLT1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against XYLT1 was raised in rabbit using the Human XYLT1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-46686A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | XYLT1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., 0.02% Sodium Azide, 0.1M Glycine, 0.1M NaHCO3 |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human XYLT1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86Y38 |
Uniprot Id
Q86Y38
Target Species
Human
Target Name
XYLT1
Target Full Name
Xylosyltransferase 1
Target Function
Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal embryonic and postnatal skeleton development, especially of the long bones. Required for normal maturation of chondrocytes during bone development, and normal onset of ossification.
Target Involvement
Desbuquois dysplasia 2 (DBQD2); Pseudoxanthoma elasticum (PXE)
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted.
Target Protein Families
Glycosyltransferase 14 family, XylT subfamily
Target Tissue Specificity
Widely expressed. Expressed at higher level in placenta, kidney and pancreas. Weakly expressed in skeletal muscle.
Target Synonyms
Beta D xylosyltransferase 1; O xylosyltransferase 1; Peptide O-xylosyltransferase 1; PXYLT1; UDP-D-xylose:proteoglycan core protein; XT-I; XT1; XTI; Xylosyltransferase 1; Xylosyltransferase I; xylosyltransferase iota; XylT-I; XYLT1; XYLT1_HUMAN
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