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The antibody against YARS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 228-477 of human YARS2 (NP_001035526.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against YARS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 228-477 of human YARS2 (NP_001035526.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01837A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | YARS2 |
| Target Synonyms | TYRRS; CGI-04; MLASA2; MT-TYRRS; YARS2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, HepG2, HT-29, Mouse brain, SKOV3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 228-477 of human YARS2 (NP_001035526.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y2Z4 | Immunogen Sequence |
Uniprot Id
Q9Y2Z4
Target Species
Human
Target Name
YARS2
Target Full Name
Tyrosine--tRNA ligase, mitochondrial
Target Function
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Target Involvement
Myopathy with lactic acidosis and sideroblastic anemia 2 (MLASA2)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Synonyms
CGI 04; FLJ13995; mitochondrial; MLASA2; mt TyrRS; SYYM_HUMAN; Tyrosine tRNA ligase 2 mitochondrial; Tyrosine tRNA ligase; Tyrosine tRNA ligase mitochondrial; Tyrosine--tRNA ligase; Tyrosyl tRNA synthetase 2 mitochondrial; Tyrosyl tRNA synthetase mitochondrial precursor; Tyrosyl-tRNA synthetase; TyrRS; YARS 2; YARS2
Target Background
This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2).
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