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The antibody against YARS2 was raised in rabbit using the Recombinant Human Tyrosine--tRNA ligase, mitochondrial protein (228-477AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against YARS2 was raised in rabbit using the Recombinant Human Tyrosine–tRNA ligase, mitochondrial protein (228-477AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human testis tissue using YARS2 Antibody at dilution of 1:1002
| Cat.No | ADC-43988A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | YARS2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tyrosine--tRNA ligase, mitochondrial protein (228-477AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y2Z4 |
Uniprot Id
Q9Y2Z4
Target Species
Human
Target Name
YARS2
Target Full Name
Tyrosine--tRNA ligase, mitochondrial
Target Function
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Target Involvement
Myopathy with lactic acidosis and sideroblastic anemia 2 (MLASA2)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Synonyms
CGI 04; FLJ13995; mitochondrial; MLASA2; mt TyrRS; SYYM_HUMAN; Tyrosine tRNA ligase 2 mitochondrial; Tyrosine tRNA ligase; Tyrosine tRNA ligase mitochondrial; Tyrosine--tRNA ligase; Tyrosyl tRNA synthetase 2 mitochondrial; Tyrosyl tRNA synthetase mitochondrial precursor; Tyrosyl-tRNA synthetase; TyrRS; YARS 2; YARS2
Target Background
This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2).
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