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The antibody against YEATS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 130-331 of human YEATS2 (NP_060493.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against YEATS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 130-331 of human YEATS2 (NP_060493.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10581A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | YEATS2 |
| Target Synonyms | FAME4; YEATS2 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 130-331 of human YEATS2 (NP_060493.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9ULM3 | Immunogen Sequence |
Uniprot Id
Q9ULM3
Target Species
Human
Target Name
YEATS2
Target Full Name
YEATS domain-containing protein 2
Target Function
Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.
Target Subcellular Location
Nucleus.
Target Synonyms
FLJ10201; FLJ12841; FLJ13308; FLJ33401; FLJ34335; KIAA1197; YEATS domain containing 2; YEATS domain-containing protein 2; Yeats2; YETS2_HUMAN
Target Background
Summary: The protein encoded by this gene is a scaffolding subunit of the ATAC complex, which is a complex with acetyltransferase activity on histones H3 and H4. Alternative splicing results in multiple transcript variants encoding different isoforms.
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