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The antibody against YKT6 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-198 of human YKT6 (NP_006546.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against YKT6 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-198 of human YKT6 (NP_006546.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05538A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | YKT6 |
| Target Synonyms | YKT6 | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 100-198 of human YKT6 (NP_006546.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | EFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM | Uniprot ID | O15498 |
Uniprot Id
O15498
Target Species
Human
Target Name
YKT6
Target Full Name
Synaptobrevin homolog YKT6
Target Function
Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.
Target Subcellular Location
Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Note=Probably cycles through vesicles between Golgi and endosomes.
Target Protein Families
Synaptobrevin family
Target Synonyms
R SNARE; SNARE protein Ykt6; Synaptobrevin homolog YKT6; YKT 6; YKT6; YKT6 S. cerevisiae homolog of; YKT6 v SNARE homolog; YKT6 v SNARE protein; YKT6_HUMAN
Target Background
This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway.
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