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Rabbit anti-Human YY1AP1 Polyclonal Antibody

The antibody against YY1AP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human YY1AP1 (NP_060723.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03433A

The antibody against YY1AP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human YY1AP1 (NP_060723.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03433A ClonalityPolyclonal
Host SpeciesRabbitTarget NameYY1AP1
Target SynonymsGRNG; HCCA1; HCCA2; YY1AP; YY1AP1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesBxPC-3, HepG2, HT-29, Mouse liver, Rat lung, SGC-7901ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human YY1AP1 (NP_060723.2).Target SpeciesHuman
Immunogen SequenceMGFSNMEDDGPEEEERVAEPQANFNTPQALRFEELLANLLNEQHQIAKELFEQLKMKKPSAKQQKEVEKVKPQCKEVHQTUniprot IDQ9H869
Background Information
  • Uniprot Id

    Q9H869

  • Target Species

    Human

  • Target Name

    YY1AP1

  • Target Full Name

    YY1-associated protein 1

  • Target Function

    Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication. Enhances transcription activation by YY1. Plays a role in cell cycle regulation.

  • Target Involvement

    Grange syndrome (GRNG)

  • Target Subcellular Location

    Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus.

  • Target Tissue Specificity

    Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.

  • Target Synonyms

    FLJ10875; FLJ13914; GRNG; HCCA1; HCCA2; Hepatocellular carcinoma susceptibility protein; Hepatocellular carcinoma-associated protein 2; OTTHUMP00000033475; OTTHUMP00000033476; OTTHUMP00000200831; OTTHUMP00000200832; OTTHUMP00000200833; OTTHUMP00000200836; YAP; YY1-associated protein 1; YY1AP; YY1AP1; YYAP1_HUMAN

  • Target Background

    Predicted to enable transcription coregulator activity. Involved in cell differentiation; cell population proliferation; and regulation of cell cycle. Located in fibrillar center and nucleoplasm. Colocalizes with Ino80 complex.

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