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The antibody against ZCCHC8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ZCCHC8 (NP_060082.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ZCCHC8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ZCCHC8 (NP_060082.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00961A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZCCHC8 |
| Target Synonyms | PFBMFT5; ZCCHC8 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, Mouse thymus | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ZCCHC8 (NP_060082.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6NZY4 | Immunogen Sequence |
Uniprot Id
Q6NZY4
Target Species
Human
Target Name
ZCCHC8
Target Full Name
Zinc finger CCHC domain-containing protein 8
Target Function
Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex that is involved in the surveillance and turnover of aberrant transcripts and non-coding RNAs. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. May be involved in pre-mRNA splicing. It is required for 3'-end maturation of telomerase RNA component (TERC), TERC 3'-end targeting to the nuclear RNA exosome, and for telomerase function.
Target Subcellular Location
Nucleus, nucleoplasm. Nucleus.
Target Protein Families
ZCCHC8 family
Target Synonyms
DKFZp434E2220; ZCCHC8; ZCHC8_HUMAN; Zinc finger CCHC domain containing 8; Zinc finger CCHC domain containing protein 8; Zinc finger CCHC domain-containing protein 8
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