Rabbit anti-Human ZEB2 Polyclonal Antibody

The antibody against ZEB2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1050-1214 of human ZEB2 (NP_055610.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-12422A

Number

Cat.No	ADA-12422A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ZEB2
Target Synonyms	SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1; ZEB2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse brain, Mouse liver	Application	ELISA, WB, IHC-P

Cat.No

ADA-12422A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ZEB2

Target Synonyms

SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1; ZEB2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse brain, Mouse liver

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1050-1214 of human ZEB2 (NP_055610.1).	Target Species	Human
Immunogen Sequence	SGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM	Uniprot ID	O60315

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1050-1214 of human ZEB2 (NP_055610.1).

Target Species

Human

Immunogen Sequence

SGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM

Uniprot ID

O60315

Background Information

Uniprot Id

O60315
Target Species

Human
Target Name

ZEB2
Target Full Name

Zinc finger E-box-binding homeobox 2
Target Function

Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin. Represses expression of MEOX2.
Target Involvement

Mowat-Wilson syndrome (MOWS)
Target Subcellular Location

Nucleus. Chromosome.
Target Protein Families

Delta-EF1/ZFH-1 C2H2-type zinc-finger family
Target Synonyms

FLJ42816; HSPC082; KIAA0569; SIP 1; SIP1; Smad Interacting Protein 1; Smad-interacting protein 1; SMADIP 1; SMADIP1; ZEB 2; Zeb2; ZEB2_HUMAN; Zfhx1b; ZFHX1B protein; Zfx1b; Zinc finger E box binding protein 2; Zinc finger E-box-binding homeobox 2; Zinc finger homeobox 1b; zinc finger homeobox protein 1; Zinc finger homeobox protein 1b
Target Background

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.

Rabbit anti-Human ZEB2 Polyclonal Antibody

Specifications

Immunogen Information

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